Roskamp Institute Seeks To Help A Rapidly Aging Population

The world is aging at a steady and inexorable pace thanks to major advances in the fields of medicine, nutrition and public hygiene. The quality of life has improved dramatically over the past few decades and various diseases have been eliminated during the same period. However, a rapidly aging population also brings about various demographic challenges. Not only do people desire to live better and not just longer lives but governments also fear increasing public health costs that arise from having an elderly population. While age related deterioration is the unintended disadvantage of leading a long life, it doesn’t always have to be this way. The Roskamp Institute based in Sarasota, Florida is at the forefront of the march towards healthy aging. 

It is an unfortunate but scientific fact that the brain begins to shrink as one age and this results in a curtailment of various bodily and mental functions. There are also changes in the structure of the brain that reduce the ability to communicate between neurons. Further, there is also a reduction in blood supply to the brain because arteries become narrow. In addition to all of the above, the brain also gets damaged by free radicals which are responsible for inflammation in tissues. All in all, it becomes very difficult for a very elderly person to enjoy a rich and varied life since many complex functions can no longer be performed by the body and mind. Most degenerative diseases of the brain appear at around 60 years of age, with the chances of getting them increasing exponentially as one grows older.

 The Roskamp Institute’s Dr. Michael Mullan has built up a formidable reputation in the field of Alzheimers research and he has devoted his efforts to finding solutions to various neurodegenerative disorders by developing effective drug therapies for them. Addiction is another area of interest at this institute and this too has very important ramifications for society. The research teams at this institute have already been able to greatly increase our understanding of these diseases, leaving the way open to finding cures in the future. As of now, it has become possible to reduce the severity of symptoms even though cures are not always possible. Identifying the symptoms correctly and diagnosing diseases during their early stages will ensure that treatments can be started as quickly as possible.

It is safe to say that it is only a matter of time before drugs will easily be available for various neurological based psychiatric and degenerative diseases. In fact, the great importance of the path breaking work undertaken at this institute is underlined by the fact that it receives a great deal of funding from many private and government sources. 

Dr. Michael Mullan is introducing a very important aspect regarding Alzheimer's disease  which is very dangerous disease for both man and women in old age.

Factors Causing Alzheimer’s Disease

Many scientists don’t yet entirely discern what causes Alzheimer's disorder, but it has become increasingly understandable that it develops because of several events happening i n succession that make a place in the brain. Dr. Michael Mullan, (CEO) Roskamp Institute, Florida has devoted a lifetime searching for the cause of this disease. As per him, the cause is a mixture of environmental, genetic and lifestyle factors. Because people’s standard of living differs, the probability of any one of these factors in increasing or decreasing the hazard of developing Alzheimer's differs from one to one.

The abnormal protein bunches, inclusions, in the brain tissue are always associated with the disease, but there could be another underlying process that is actually causing the Alzheimer's - scientists are not yet certain.

This disorder has three stages:

• Preclinical
• Mild cognitive impairment
• Dementia.

Changes In The Brain

One of the bulky mysteries of Alzheimer’s disorder is why it largely strikes older adults. Study on how the brain changes normally with age is shedding medium of vision on this interrogation. For example, scientists are acquisition of knowledge how age-of the same nature changes in the brain may disadvantage neurons and grant or bestow (as a share) to Alzheimer’s injury.

Role Of Genetics

The more researchers learn about this disorder, the more they analyze that genes play a crucial role in its development. As per London based Roskamp Institute, Alzheimer is a rare sort of disorder. It occurs to people at an age of 30 to 60 and represents less than 5 percent of all the people who have this disorder. Most cases of attack by this disease are changes in one of three known genes inherited from a father or mother.

Most people with this disorder have “late-onset” Alzheimer’s, which normally comes into action after people cross 60. Many studies have linked the apolipoprotein E (APOE) gene to slow-attack Alzheimer’s. One of them, APOE ε4, increases the person’s probability of getting the disorder. However, carrying the APOE ε4 cast of the gene does not actually mean that it will definitely cause the dementia. Also, a probability still remains that people without APOE ε4 may get this disease. Most experts believe that more genes may contribute to the occurrence of slow-attack Alzheimer’s. Scientists around the world are seeking for these genes, and have discovered a variety of genes that may be contributors to the occurrence of this disease.

Women More Prone To Alzheimer

Many, but not all, studies have found that women have a higher danger for Alzheimer's disorder than men. It is certainly clear that women live longer as compared to men, but age alone does not seem to unfold the increased frequent disease occurrence in women. The frequent occurrences of Alzheimer’s distemper in women have led to consideration about the role of estrogen in Alzheimer's disease.

Other Factors

Factors including diabetes, high blood pressure and high cholesterol increase the risk of stroke, which can lead to another type of disorder. Low education is also one of the reasons.

Roskamp Institute – Attempting Alzheimer through Objective Researches

Health is a gift for the mind, body and soul and is the true wealth to cherish. However, this gifted wealth often gets aberrated due to disease conditions. If the person is lucky enough, then he can get cured with the available line of drugs; however, there are certain illnesses, the cures for which have remained elusive after long and dedicated researches.

Alzheimer disease is characterized by most of the dementia symptoms such as the memory degradation, visual losses, locomotor losses and identification problems among others. The pitiful aspect of Alzheimer is that most of the symptoms and manifestations are sidelined as that of old age in a very commonly accepted norm, thus leaving the aged person to struggle. The more educated and aware societies of the world have shown greater rates of diagnosis, if not the incidence.

Finding out the fundamental factors

The med community has been engaged in quality and deeper researches so as to establish the reasons, but the cure is still far away. There have been some authentic insight, of course, from some noted quarters like the Roskamp Institute of US. This not for profit research institute has under the inspiring leadership of Michael Mullan produced valuable leads as for understanding some correlations between Alzheimer and associated factors.

Dr Mullan is considered a global authority on Alzheimer research because of his pioneering studies that helped establish the role of beta amyloid protein which he found is overproduced due to a genetic inconsistency. Greater the production of this protein, greater would be the progression rate of the disease.

 Running associated programs for holistic research

Michael Mullan is the CEO of Sarasota based Roskamp Institute and has been guiding the next phase of the researches to bring out more insights through dedicated programs of direct consonances. The institute runs its ‘Vision Research Program’ that is oriented towards studying the visual impairments in the dementia and Alzheimer by studying the patterns of visual cortex and optical nerves over the time in the Alzheimer patients.

The Institute also runs Memory Clinics where objective counseling is offered with the aim of arresting the disease progression. The Roskamp Institute also studies the effect of the potential risk factors as for Alzheimer disease such as the head injuries, family history, depression and hypertension among others. Such correlations have proved to be beneficial as for prescribing the care suggestions for the person where already the onset has been diagnosed.

Carrying out effective yet ethical clinical trials -

The research maneuvers of the Institute are complemented by the ‘Clinical Trials Division’ of it which is an attempt to collect the most authentic of the databases from the willing volunteers in an ethical manner. The volunteers are offered potential cures free of cost together with effective cushioning against the side effects.

 Michael Mullan has established some of the finest standards in this Sarasota institute which is escorting the care and cure attempts with the best of the Biomedical Researcher community at its end. The findings of this Institute have been validated by noted journals that demonstrate the efficacies.

Alzheimer – Memory Loss that can Lead to Death

Alzheimer is a disease which has surfaced more during the recent years. It is caused by the protein compounds that are accumulated in the brain. Since it is a neuro-degenerative disease, the person gets worse as time passes by. The disease is recognized by the early onset of short term memory loss. This can lead to death as the functions of the body are lost one at a time.

There are many medical institutes that are researching on the Alzheimer’s disease. The researchers believe that it is mostly caused by genetic disorder. Michael Mullan is one of the most popular researchers who studied the cause and cure of Alzheimer. He is well trained in molecular genetics to perform gene research with respect to the disease. He currently holds the position of President and CEO in Roskamp Institute which is located in Florida. Dr.Mullan made ground breaking research and presented over 200 articles on Alzheimer which also includes the treatment for the disease.

Dr. Mullan having experience of more than 20 years in biotechnology, invented patents that used APP mutations. He worked for the causes of this disease along with its cure by receiving grants from federal organizations. He was the first person to identify the genetic cause of the disease. It was established that people with gene mutations present in TREM2 had a higher risk of getting affected by the Alzheimer disease.

There are medications which can help in treating the patients and can slow down the progress of Alzheimer, but a sure cure for the disease is still a work under progress. Roskamp is the closest institute which is on the way to finding a cure. The drug, Nilvadipine, was administered for treating hypertension, which is identified as one of the reasons that cause the disease. This drug has been proved to stop the protein production in the brain. Amyloid is considered to be a tombstone and hence the drug was developed to stop its production all together.

Michael Mullan Roskamp Institute diagnoses patients with Alzheimer and offer clinical trial for the drug which was developed. Observations were made in the genes and the medical history of the relatives in order to diagnose the disease. Medical imaging like MRI and PET are used to rule out other forms of dementia. This type of diagnosis can be made only after the onset of the disease. Early diagnosis include cerebrospinal fluid test for the presence of amyloid. This spinal tap predicts the onset of the disease which is about 94% accurate. 

There is no drug at present to prevent the onset of this disease. But, various studies prove that measures like dieting, intellectual activities and reducing cholesterol level can be done to decrease the chance of being affected by Alzheimer’s disease.

MICHAEL MULLAN AND HIS ALZHEIMER’S RESEARCH AT FLORIDA

All about the Great Researcher

Biomedical researcher Michael Mullan has conducted Alzheimer’s disease which was based on the identification of the Swedish Mutation which is present in the familial form. This person is trained in England as a physician and received his medical degree in 1995 and PhD in molecular genetics from London University. Currently he is working as a CEO and the president of the Roskamp Institute. He has published more than 200 papers.

He had conducted the important medical research in neurodegenerative disorders. He is a very experienced person and is also imparting knowledge on the subject dementia. He is working in research centers and medical institutions too.

Fighting Alzheimer’s Disease

It was a very great study by him at Roskamp Institute at Sarasota Florida in which he discovered that that all the disorders which are genetic are found to be in amyloidal genes. The whole of this research was basically based on the Amyloid and now is categorized as a very important part of the Alzheimer’s disease. It is also found that this disease is commonly found at the ages of 50 to 70. All the studies which were conducted followed by a result that the small protein amyloid when accumulates can contribute to the series of things which can lead to cognitive declination and degeneration.

The research was going-on on mice which had the errors in it like a human who is on the early stage of the disorder called Alzheimer. This study on the mice  has gave the researchers an idea about how a small protein called amyloid can cause disorder  and can lead to the death of neurons. Many of the pharmaceutical labs and academic labs have this kind of mice. So they used to test many such drugs on the mice which can prevent them from this disease. Just to give a solution to this problem, many researches were conducted. This disease actually came from a family of a woman Carol Jennings from England. Her family had this genetic problem in which fifty percent that is half of the off springs who used to take birth in their family were having this disease at an early stage. And then she started for the search of the people who were interested to carry on the research on Alzheimer’s disease. By doing this she not only helped her family but also helped the people who were suffering from this disease.

At all the positions on which Michael Mullan worked, he made efforts to research on the cure of neurodegenerative disorders for the long-term.

The Roskamp institute at which he worked was always working on the fact that they wanted to understand the causes and the perfect cures for neuropsychiatric and neurodegenerative disorders and the kind of addictions that happens due to that. This institute had utilized all the range of scientific and technological approaches, so that they can understand its causes and the kind of various therapies for curing this disorder with the emphasis laid on the Alzheimer’s disease.

For More Details Visit Here: -- Michael Mullan Roskamp